Serum bilirubin may serve as a marker for increased heme oxygenase activity and inducibility in tissues--a rationale for the versatile health protection associated with elevated plasma bilirubin.

Abstract

Unconjugated bilirubin functions intracellularly as a potent inhibitor of NADPH oxidase complexes, and albumin-bound bilirubin contributes significantly to the oxidant scavenging activity of plasma. So it is not surprising that serum levels of bilirubin have been found to correlate inversely with risk for vascular diseases and a host of other disorders… (More)
DOI: 10.1016/j.mehy.2013.07.013

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Cite this paper

@article{McCarty2013SerumBM, title={Serum bilirubin may serve as a marker for increased heme oxygenase activity and inducibility in tissues--a rationale for the versatile health protection associated with elevated plasma bilirubin.}, author={Mark Frederick McCarty}, journal={Medical hypotheses}, year={2013}, volume={81 4}, pages={607-10} }