Serum apoptotic caspase activity in chronic hepatitis C and nonalcoholic Fatty liver disease.

@article{Papatheodoridis2010SerumAC,
  title={Serum apoptotic caspase activity in chronic hepatitis C and nonalcoholic Fatty liver disease.},
  author={G V Papatheodoridis and Emilia Hadziyannis and Emmanuel A Tsochatzis and Anastasia Georgiou and Georgia Kafiri and Dina G. Tiniakos and Katerina Margariti and Spilios G Manolakopoulos and Emanuel K Manesis and Athanasios J. Archimandritis},
  journal={Journal of clinical gastroenterology},
  year={2010},
  volume={44 4},
  pages={e87-95}
}
BACKGROUND Apoptotic caspases are substantially activated in liver and serum caspase activity has been suggested as a marker of early liver injury. AIM To investigate whether serum levels of caspase-generated fragments of cytokeratin-18 are associated with the severity of histologic lesions in chronic hepatitis C virus (HCV) infection and nonalcoholic fatty liver disease (NAFLD). METHODS We included 134 patients with chronic HCV infection and 58 patients with NAFLD, who consecutively… CONTINUE READING
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