Serum anticyclic citrullinated protein antibody titers are correlated with the response to biological agents in patients with rheumatoid arthritis

@inproceedings{Takahashi2014SerumAC,
  title={Serum anticyclic citrullinated protein antibody titers are correlated with the response to biological agents in patients with rheumatoid arthritis},
  author={Ryo Takahashi and Sakiko Isojima and Masayu Umemura and Yoko Miura and Nao Oguro and Syo Ishii and Shinya Seki and Takahiro Tokunaga and Hiroyuki Tsukamoto and Hidekazu Furuya and Ryo Yanai and Tsuyoshi Kasama},
  booktitle={Open access rheumatology : research and reviews},
  year={2014}
}
Anticyclic citrullinated protein antibody (ACPA) is known as an important indicator for diagnosis of rheumatoid arthritis (RA). Our aim was to examine the relationship between the serum ACPA titer at baseline and responsiveness to biological agents (antagonists of either tumor necrosis factor or interleukin 6) in patients with RA. ACPA was measured using second-generation chemiluminescent enzyme immunoassay. Disease activity was assessed using disease activity scores 28. Fifty-seven RA patients… CONTINUE READING
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