Serum and urine interleukin-6 and transforming growth factor-beta1 in young infants with pyelonephritis

@article{Galanakis2006SerumAU,
  title={Serum and urine interleukin-6 and transforming growth factor-beta1 in young infants with pyelonephritis},
  author={Emmanouil Galanakis and Mar{\'i}a Bitsori and Helen Dimitriou and Christina A. Giannakopoulou and Nickolaos S. Karkavitsas and Maria C Kalmanti},
  journal={International Urology and Nephrology},
  year={2006},
  volume={39},
  pages={581-585}
}
Cytokines are involved both in the acute response during pyelonephritis and in the progression to renal scarring. The aim of the present study was to assess the pro-inflammatory interleukin-6 (IL-6) and the anti-inflammatory pro-fibrotic transforming growth factor-beta1 (TGF-beta) in very young infants with pyelonephritis. Serum and urine concentrations of IL-6 and TGF-beta1 were determined by enzyme immunoassay in infants with acute pyelonephritis before antibiotic treatment and in infants… CONTINUE READING
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