Serum and urinary cell-free MiR-146a and MiR-155 in patients with systemic lupus erythematosus.

@article{Wang2010SerumAU,
  title={Serum and urinary cell-free MiR-146a and MiR-155 in patients with systemic lupus erythematosus.},
  author={Gang Wang and L O Tam and Edmund Kwok-Ming Li and Bonnie Ching-Ha Kwan and Kai-Ming Chow and Cathy Choi-Wan Luk and Philip Kam-tao Li and C. H. Szeto},
  journal={The Journal of rheumatology},
  year={2010},
  volume={37 12},
  pages={2516-22}
}
OBJECTIVE Recent studies showed that micro-RNA play important roles in the pathogenesis of autoimmune diseases. We studied the levels of miR-146a and miR-155 in the serum and urinary supernatant of patients with systemic lupus erythematosus (SLE). METHODS The serum and urinary supernatant levels of miR-146a and miR-155 were determined by real-time quantitative polymerase chain reaction in 40 patients with SLE and 30 healthy controls. RESULTS Compared to controls, serum miR-146a and miR-155… CONTINUE READING
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