Serum and tissue profiling in bladder cancer combining protein and tissue arrays.

@article{OrenesPiero2010SerumAT,
  title={Serum and tissue profiling in bladder cancer combining protein and tissue arrays.},
  author={Esteban Orenes-Pi{\~n}ero and Rodrigo Barderas and Daniel Rico and Jos{\'e} Ignacio Casal and David Gonz{\'a}lez-Pisano and Jos{\'e} Alejandro Navajo and Ferr{\'a}n Algaba and Josep Mar{\'i}a Piulats and Marta S{\'a}nchez-Carbayo},
  journal={Journal of proteome research},
  year={2010},
  volume={9 1},
  pages={164-73}
}
Aiming at identifying biomarkers for bladder cancer, the serum proteome was explored in a pilot study through a profiling approach using protein arrays. Supervised analyses identified a panel 171 immunogenic proteins differentially expressed between patients with bladder cancer (n = 12) and controls without the disease (n = 10). The microanatomical expression patterns of novel immunogenic proteins, especially dynamin and clusterin, were found significantly associated with histopathologic… CONTINUE READING