Serum and liver enzymes of collagen synthesis in hepatic murine schistosomiasis mansoni.

@article{Bolarin1985SerumAL,
  title={Serum and liver enzymes of collagen synthesis in hepatic murine schistosomiasis mansoni.},
  author={D. M. Bolarin and K A Barker and George Charles Fuller},
  journal={Transactions of the Royal Society of Tropical Medicine and Hygiene},
  year={1985},
  volume={79 6},
  pages={
          826-30
        }
}
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Liver collagen synthesis in murine schistosomiasis.
TLDR
The studies show the synthesis of collagen in a reproducible animal model of the most prevalent form of human liver fibrosis, which results from an inflammatory granulomatous host response to Schistosoma mansoni ova in portal tracts, rather than from direct lover cell injury as with carbon tetrachloride-induced Liver fibrosis.
Liver immunoreactive prolyl hydroxylase protein in human primary hepatocellular carcinoma.
TLDR
The findings of this study provide a basis for the elevated serum values of this intracellular enzyme of collagen synthesis in patients with primary hepatocellular carcinoma and the data indicate that this enzyme may be elevated to compensate for an increased rate of collagen synthesisation in the malignant liver tissue.
Activities of prolyl hydroxylase, lysyl hydroxylase, collagen galactosyltransferase and collagen glucosyltransferase in the liver of rats with hepatic injury.
TLDR
The results indicate that the increased enzyme activities cannot be explained simply by an increase in the number of collagen-producing cells having similar enzyme activity patterns to those of the cells initially present in the liver.
Enzymes of collagen synthesis and type iii procollagen amino‐propeptide in serum from nigerians with hepatocellular carcinoma and other malignant diseases
TLDR
A high correlation was found between the values for the three assays both in primary hepatocellular carcinoma and in the whole series of malignant diseases, which suggest that primary and secondary malignant neoplasms of the liver have a high rate of collagen synthesis.
Assay of collagen-galactosyltransferase and collagen-glucosyltransferase activities and preliminary characterization of enzymic reactions with transferases from chick-embryo cartilage.
TLDR
Preliminary characterization of the transferases from chick embryo cartilage indicated that the galactosyltransferase did not catalyze the transfer of galactose to free hydroxylysine, and manganese was found to be far more effective than any other metal tested.
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