Serum and liver enzymes of collagen synthesis in hepatic murine schistosomiasis mansoni.

  title={Serum and liver enzymes of collagen synthesis in hepatic murine schistosomiasis mansoni.},
  author={D. M. Bolarin and K A Barker and George Charles Fuller},
  journal={Transactions of the Royal Society of Tropical Medicine and Hygiene},
  volume={79 6},
Diagnostic Markers for Schistosome-Mediated Liver Disease
It is suggested that within the context of a youth-services agency using a mobile application, using a tablet or computer to provide real-time information about an individual’s educational needs is a viable process.
Experimental murine schistosomiasis: reduced hepatic morbidity after pre- and/or post-infection treatment with ibuprofen or diclofenac sodium.
The results indicate that the treatment of S. mansoni-infected mice with ibuprofen or diclofenac sodium was effective in reducing the severity of infection and in attenuating hepatic fibrosis, particularly when the treatment was started early in relation to the time of infection.
Human lysyl hydroxylase isoforms : multifunctionality of human LH3 and the amino acids important for its collagen glycosyltransferase activities
The sequence alignment of LH isoforms from different species revealed that there are 29 amino acids conserved between human LH3, mouse LH3 and C. elegans LH sequences, showing the importance of this motif for collagen glycosyltransferases and suggesting that it might serve as the Mn2+ binding site in collagen.


Liver collagen synthesis in schistosomiasis mansoni.
Liver collagen synthesis in murine schistosomiasis.
The studies show the synthesis of collagen in a reproducible animal model of the most prevalent form of human liver fibrosis, which results from an inflammatory granulomatous host response to Schistosoma mansoni ova in portal tracts, rather than from direct lover cell injury as with carbon tetrachloride-induced Liver fibrosis.
Liver immunoreactive prolyl hydroxylase protein in human primary hepatocellular carcinoma.
The findings of this study provide a basis for the elevated serum values of this intracellular enzyme of collagen synthesis in patients with primary hepatocellular carcinoma and the data indicate that this enzyme may be elevated to compensate for an increased rate of collagen synthesisation in the malignant liver tissue.
Activities of prolyl hydroxylase, lysyl hydroxylase, collagen galactosyltransferase and collagen glucosyltransferase in the liver of rats with hepatic injury.
The results indicate that the increased enzyme activities cannot be explained simply by an increase in the number of collagen-producing cells having similar enzyme activity patterns to those of the cells initially present in the liver.
Enzymes of collagen synthesis and type iii procollagen amino‐propeptide in serum from nigerians with hepatocellular carcinoma and other malignant diseases
A high correlation was found between the values for the three assays both in primary hepatocellular carcinoma and in the whole series of malignant diseases, which suggest that primary and secondary malignant neoplasms of the liver have a high rate of collagen synthesis.
Assay of collagen-galactosyltransferase and collagen-glucosyltransferase activities and preliminary characterization of enzymic reactions with transferases from chick-embryo cartilage.
Preliminary characterization of the transferases from chick embryo cartilage indicated that the galactosyltransferase did not catalyze the transfer of galactose to free hydroxylysine, and manganese was found to be far more effective than any other metal tested.