Serum and liver enzymes of collagen synthesis in hepatic murine schistosomiasis mansoni.
@article{Bolarin1985SerumAL, title={Serum and liver enzymes of collagen synthesis in hepatic murine schistosomiasis mansoni.}, author={D. M. Bolarin and K A Barker and George Charles Fuller}, journal={Transactions of the Royal Society of Tropical Medicine and Hygiene}, year={1985}, volume={79 6}, pages={ 826-30 } }
4 Citations
Enzyme markers of collagen synthesis in carbon tetrachloride-induced fibrosis and during colchicine modification of CCl4-induced liver injury.
- BiologyExperimental and molecular pathology
- 1987
Diagnostic Markers for Schistosome-Mediated Liver Disease
- Biology, Medicine
- 2010
It is suggested that within the context of a youth-services agency using a mobile application, using a tablet or computer to provide real-time information about an individual’s educational needs is a viable process.
Experimental murine schistosomiasis: reduced hepatic morbidity after pre- and/or post-infection treatment with ibuprofen or diclofenac sodium.
- Medicine, BiologyAnnals of tropical medicine and parasitology
- 1995
The results indicate that the treatment of S. mansoni-infected mice with ibuprofen or diclofenac sodium was effective in reducing the severity of infection and in attenuating hepatic fibrosis, particularly when the treatment was started early in relation to the time of infection.
Human lysyl hydroxylase isoforms : multifunctionality of human LH3 and the amino acids important for its collagen glycosyltransferase activities
- Biology, Chemistry
- 2002
The sequence alignment of LH isoforms from different species revealed that there are 29 amino acids conserved between human LH3, mouse LH3 and C. elegans LH sequences, showing the importance of this motif for collagen glycosyltransferases and suggesting that it might serve as the Mn2+ binding site in collagen.
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The findings of this study provide a basis for the elevated serum values of this intracellular enzyme of collagen synthesis in patients with primary hepatocellular carcinoma and the data indicate that this enzyme may be elevated to compensate for an increased rate of collagen synthesisation in the malignant liver tissue.
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The results indicate that the increased enzyme activities cannot be explained simply by an increase in the number of collagen-producing cells having similar enzyme activity patterns to those of the cells initially present in the liver.
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