Serum and knee synovial fluid matrix metalloproteinase-13 and tumor necrosis factor-alpha levels in patients with late-stage osteoarthritis.

@article{zler2016SerumAK,
  title={Serum and knee synovial fluid matrix metalloproteinase-13 and tumor necrosis factor-alpha levels in patients with late-stage osteoarthritis.},
  author={Kenan {\"O}zler and Erdem Aktaş and Çiğdem Atay and Barış Yılmaz and Murat Arıkan and Şafak G{\"u}ng{\"o}r},
  journal={Acta orthopaedica et traumatologica turcica},
  year={2016},
  volume={50 3},
  pages={
          356-61
        }
}
OBJECTIVE The aim of this study was to compare serum and synovial fluid levels of matrix metalloproteinase-13 (MMP-13) and tumor necrosis factor-alpha (TNF-α) in 2 stages of osteoarthritis, and investigate their correlation with Western Ontario and McMaster Universities Arthritis Index (WOMAC) scores. METHODS Forty-two patients (mean age: 64±8.8 years) with grade 3 and grade 4 knee osteoarthritis according to Kellgren-Lawrence criteria were enrolled in the study and underwent total knee… CONTINUE READING

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Review of Prospects of Biological Fluid Biomarkers in Osteoarthritis

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  • 2017
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