Serum- and glucocorticoid-regulated kinase (SGK1) gene and blood pressure.

  title={Serum- and glucocorticoid-regulated kinase (SGK1) gene and blood pressure.},
  author={Andreas Busjahn and Atakan Aydin and R Peter Uhlmann and Christine Krasko and Sylvia B{\"a}hring and Tamas Szelestei and Yuxi Feng and Stephan Dahm and Arya M. Sharma and Friedrich C. Luft and Florian Lang},
  volume={40 3},
The serum- and glucose-regulated kinase (SGK1) gene has recently been identified as an important aldosterone-induced protein kinase that mediates trafficking of the renal epithelial Na(+) channel (ENaC) to the cell membrane. Thus, SGK1 is an appealing candidate for blood pressure regulation and possibly essential hypertension. To test this hypothesis, we recruited monozygotic (126 pairs) and dizygotic (70 pairs) normotensive twin subjects and parents of dizygotic twins. Blood pressure was… CONTINUE READING