Serum and follicular fluid levels of insulin-like growth factor I (IGF-I), IGF-II, and IGF-binding protein-1 and -3 during the normal menstrual cycle.

@article{Dessel1996SerumAF,
  title={Serum and follicular fluid levels of insulin-like growth factor I (IGF-I), IGF-II, and IGF-binding protein-1 and -3 during the normal menstrual cycle.},
  author={H J Thierry van Dessel and Yasmin A Chandrasekher and Oi Wah Stephanie Yap and Peng Lee and Raymond L. Hintz and Gerarda H Faessen and Didi D M Braat and Bart C. J. M. Fauser and Linda C. Giudice},
  journal={The Journal of clinical endocrinology and metabolism},
  year={1996},
  volume={81 3},
  pages={1224-31}
}
Insulin-like growth factors (IGFs) and their binding proteins (IGFBPs) have important regulatory functions in ovarian follicular development. Although most studies have investigated the IGF system in ovarian cells in vitro, investigation of the IGF system in the peripheral circulation and in follicles of varying sizes throughout the menstrual cycle in large numbers of subjects has been lacking. In the current study we performed daily IGF-I, IGF-II, IGFBP-1, and IGFBP-3 measurements in 9 healthy… CONTINUE READING