Serum and bronchoalveolar lavage of N-terminal type III procollagen peptides in idiopathic pulmonary fibrosis.

@article{Low1992SerumAB,
  title={Serum and bronchoalveolar lavage of N-terminal type III procollagen peptides in idiopathic pulmonary fibrosis.},
  author={Robert B. Low and M S Giancola and Talmadge E. King and Jane Chapitis and Pamela M. Vacek and Gerald S. Davis},
  journal={The American review of respiratory disease},
  year={1992},
  volume={146 3},
  pages={701-6}
}
Collagen deposition is a prime determinant of clinical course in idiopathic pulmonary fibrosis (IPF). Identification of a marker of connective tissue metabolism would significantly enhance the ability to stage the disease and monitor the course of these patients. Prior studies of IPF have indicated that N-terminal Type III procollagen peptide (N-PIIIP) levels in blood and bronchoalveolar lavage BAL fluid are elevated. We hypothesized that elevated levels of procollagen peptides are a marker of… CONTINUE READING

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