Serum and Adipose Tissue mRNA Levels of ATF3 and FNDC5/Irisin in Colorectal Cancer Patients With or Without Obesity

@inproceedings{Zhu2018SerumAA,
  title={Serum and Adipose Tissue mRNA Levels of ATF3 and FNDC5/Irisin in Colorectal Cancer Patients With or Without Obesity},
  author={Huijuan Zhu and Meijuan Liu and Nianrong Zhang and Hui Q. Pan and Guole Lin and Naishi Li and Linjie Wang and Hongbo Yang and Kemin Yan and Fengying Gong},
  booktitle={Front. Physiol.},
  year={2018}
}
Objectives: To explore the activating transcription factor 3 (ATF3) and fibronectin type III domain-containing protein 5 (FNDC5)/irisin protein levels in serum and mRNA levels in subcutaneous and visceral white adipose tissue (sWAT and vWAT) in normal-weight (NW) and overweight/obese (OW/OB) patients with colorectal cancer (CRC). Methods: 76 CRC patients and 40 healthy controls were recruited. Serum ATF3 and irisin levels were detected by using ELISA kits, and the mRNA expression levels in sWAT… CONTINUE READING
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