Serum amyloid A1: Structure, function and gene polymorphism.

  title={Serum amyloid A1: Structure, function and gene polymorphism.},
  author={Lei Sun and Richard D Ye},
  volume={583 1},
Inducible expression of serum amyloid A (SAA) is a hallmark of the acute-phase response, which is a conserved reaction of vertebrates to environmental challenges such as tissue injury, infection and surgery. Human SAA1 is encoded by one of the four SAA genes and is the best-characterized SAA protein. Initially known as a major precursor of amyloid A (AA), SAA1 has been found to play an important role in lipid metabolism and contributes to bacterial clearance, the regulation of inflammation and… CONTINUE READING


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