Serum amyloid A as a prognostic marker in melanoma identified by proteomic profiling.

@article{Findeisen2009SerumAA,
  title={Serum amyloid A as a prognostic marker in melanoma identified by proteomic profiling.},
  author={Peter Findeisen and Marc Zapatka and Teresa Peccerella and Heike Matzk and Michael Neumaier and Dirk Schadendorf and Selma Ugurel},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={2009},
  volume={27 13},
  pages={2199-208}
}
PURPOSE Currently known prognostic serum biomarkers of melanoma are powerful in metastatic disease, but weak in early-stage patients. This study was aimed to identify new prognostic biomarkers of melanoma by serum mass spectrometry (MS) proteomic profiling, and to validate candidates compared with established markers. PATIENTS AND METHODS Two independent sets of serum samples from 596 melanoma patients were investigated. The first set (stage I = 102; stage IV = 95) was analyzed by matrix… CONTINUE READING
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