Serum alpha-tocopherol concentration in relation to subsequent colorectal cancer: pooled data from five cohorts.

@article{Longnecker1992SerumAC,
  title={Serum alpha-tocopherol concentration in relation to subsequent colorectal cancer: pooled data from five cohorts.},
  author={Matthew Paul Longnecker and Jos{\'e} Mar{\'i}a Mart{\'i}n-Moreno and Paul Knekt and Abraham M. Y. Nomura and Steffen. Schober and Hannes Balthasar St{\"a}helin and Nicholas J Wald and K. Fred Gey and Walter C Willett},
  journal={Journal of the National Cancer Institute},
  year={1992},
  volume={84 6},
  pages={430-5}
}
BACKGROUND Vitamin E is an antioxidant that inhibits mutagenesis and cell transformation. Previous findings in five prospective epidemiologic studies suggested that the level of serum alpha-tocopherol, the predominant form of vitamin E in the blood, was lower in subjects who subsequently developed colorectal cancer than in control subjects. However, the difference was neither obvious nor statistically significant in any one of these five studies. PURPOSE To evaluate in greater detail the… CONTINUE READING

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