Serum alpha-fetoprotein and human chorionic gonadotropin in patients with seminoma.

  title={Serum alpha-fetoprotein and human chorionic gonadotropin in patients with seminoma.},
  author={Paul H. Lange and Lucien E. Nochomovitz and Juan Rosai and Elwin E. Fraley and Ben J Kennedy and Georges Bosl and J U Brisbane and William J. Catalona and J S Cochran and R H Comisarow and Kenneth B. Cummings and Jean B. Dekernion and Lawrence Henry Einhorn and Thomas R. Hakala and Michael M A Jewett and Michael R. Moore and Peter T. Scardino and John M Streitz},
  journal={The Journal of urology},
  volume={124 4},
We analyzed the case histories of 31 patients who initially had a diagnosis of seminoma and elevated serum levels of alpha-fetoprotein or human chorionic gonadotropin. We concluded that an elevated alpha-fetoprotein level is firm evidence of the presence of non-seminomatous germ cell tumor and that the patient should be treated accordingly. However, if the level of human chorionic gonadotropin alone is elevated the diagnosis may be either non-seminomatous tumor or seminoma. Patients with… CONTINUE READING
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