• Medicine
  • Published in Cancer research 1978

Serum alkaline phosphatase isoenzymes in lymphoproliferative diseases.

@article{Dulis1978SerumAP,
  title={Serum alkaline phosphatase isoenzymes in lymphoproliferative diseases.},
  author={B H Dulis and Irwin B. Wilson},
  journal={Cancer research},
  year={1978},
  volume={38 8},
  pages={
          2519-22
        }
}
A new isoenzyme of alkaline phosphatase (EC 3.1.3.1) has been reported to occur in sera from patients with lymphoproliferative diseases. This enzyme is characterized by an inability to hydrolyze cysteamine S-phosphate. We find that the 5,5'-dithobis(2-nitrobenzoic acid)-coupled assay method for cysteamine S-phosphate hydrolysis is not suitable for serum, and we were unable to confirm the existence of this isoenzyme in serum by this assay method. We were unable to detect to detect this new… CONTINUE READING