Serum adiponectin concentrations and tissue expression of adiponectin receptors are reduced in patients with prostate cancer: a case control study.

@article{Michalakis2007SerumAC,
  title={Serum adiponectin concentrations and tissue expression of adiponectin receptors are reduced in patients with prostate cancer: a case control study.},
  author={Konstantinos Michalakis and Catherine J. Williams and Nicholas S Mitsiades and Jennifer Blakeman and Sofia Balafouta-Tselenis and Aris M. Giannopoulos and Christos Socrates Mantzoros},
  journal={Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology},
  year={2007},
  volume={16 2},
  pages={308-13}
}
PURPOSE Adiponectin, an adipocyte-secreted hormone with insulin-sensitizing effects, has been inversely associated with several hormonally dependent malignancies, including breast, endometrial, and colorectal cancer. Few studies have examined serum adiponectin in relation to prostate cancer, and expression of adiponectin receptors has previously not been assessed in prostate tumors. EXPERIMENTAL DESIGN We collected plasma samples and covariate data in the context of a case-control study of… CONTINUE READING

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