Serum PBDEs and age at menarche in adolescent girls: analysis of the National Health and Nutrition Examination Survey 2003-2004.

@article{Chen2011SerumPA,
  title={Serum PBDEs and age at menarche in adolescent girls: analysis of the National Health and Nutrition Examination Survey 2003-2004.},
  author={Aimin Chen and Ethan William Chung and Emily A. DeFranco and Susan Mengel Pinney and Kim N. Dietrich},
  journal={Environmental research},
  year={2011},
  volume={111 6},
  pages={831-7}
}
BACKGROUND Polybrominated diphenyl ethers (PBDEs), widely used as flame retardants since the 1970s, have exhibited endocrine disruption in experimental studies. Tetra- to hexa-BDE congeners are estrogenic, while hepta-BDE and 6-OH-BDE-47 are antiestrogenic. Most PBDEs also have antiandrogenic activity. It is not clear, however, whether PBDEs affect human reproduction. OBJECTIVES The analysis was designed to investigate the potential endocrine disruption of PBDEs on the age at menarche in… CONTINUE READING

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