Serum N-terminal telopeptide of type I collagen as an early marker of fracture nonunion in rabbits

@inproceedings{Lin2016SerumNT,
  title={Serum N-terminal telopeptide of type I collagen as an early marker of fracture nonunion in rabbits},
  author={J Lin and Zhan-jun Shi and Ning-Jiang Shen and Jian Wang and Zao-Min Li and Jun Xiao},
  booktitle={Experimental and therapeutic medicine},
  year={2016}
}
The aim of the present study was to establish an experimental animal model of fracture nonunion, and to investigate the changes in serum biomarker concentrations in fracture nonunion. A total of 20 purebred New Zealand rabbits were divided into two group: A bone defect group and a bone fracture group. In the bone defect group, a 15-mm section of bone (including the periosteum) was removed from the mid-radius, and the medullary cavities were closed with bone wax. In the bone fracture group, the… CONTINUE READING