Serum Matrix Metalloproteinase-7 is an independent prognostic biomarker in advanced bladder cancer

Abstract

BACKGROUND Urine markers have been studied extensively but there is a lack of blood prognostic markers in bladder cancer. MMP-7 is produced by stromal cells and by tumor cells and is overexpressed in a variety of epithelial and mesenchymal tumors. In this study, we assessed with an immunoassay we developed, the prognostic value of serum MMP-7 in a series of… (More)
DOI: 10.1186/s40169-014-0031-4

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