Serum MMP-1 and TIMP-1 levels are increased in patients with psoriatic arthritis and their siblings.

Abstract

OBJECTIVE To determine matrix metalloproteinase-1 (MMP-1) and tissue-inhibitor metalloproteinase-1 (TIMP-1) serum levels in patients with psoriatic arthritis (PsA) and to compare this with their siblings and local blood donor controls. PsA is an interesting condition in which to study metalloproteinases because there are variations in the level of… (More)

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