Serum Levels of Tissue Inhibitors of Metalloproteinase 2 in Patients With Systemic Sclerosis With Duration More Than 2 Years: Correlation With Cardiac and Pulmonary Abnormalities

@article{Shahin2006SerumLO,
  title={Serum Levels of Tissue Inhibitors of Metalloproteinase 2 in
Patients With Systemic Sclerosis With Duration More Than 2
Years: Correlation With Cardiac and Pulmonary Abnormalities},
  author={Amira A. Shahin and Amani Elsawaf and Shahira Ramadan and Olfat Gamil Shaker and Mona A. Amin and Mohamed S Taha},
  journal={Mediators of Inflammation},
  year={2006},
  volume={2006},
  pages={92S - 96S}
}
In this study, we measured the serum concentration of TIMP-2 in patients with systemic sclerosis (SSc) and explored its possible correlation with cardiac and pulmonary lesions. We studied 42 patients with SSc, with duration equal to or more than 2 years. CT chest, ECG, echocardiography, and serum TIMP-2 concentration measurement using ELISA technique were performed in all patients and in 25 normal controls. The mean serum levels of TIMP-2 in patients was higher than in controls (P = .005). The… CONTINUE READING

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