Serum Levels of Interleukin-34 During Acute Rejection in Liver Transplantation.

  title={Serum Levels of Interleukin-34 During Acute Rejection in Liver Transplantation.},
  author={David San Segundo and Patricia Bolivar Ruiz and Juan Irure and Mar{\'i}a Teresa Arias-Loste and Antonio Cuadrado and A. Arias Puente and Fernando Casafont and Marcos L{\'o}pez-Hoyos and Javier Crespo and Emilio F{\'a}brega},
  journal={Transplantation proceedings},
  volume={48 9},
INTRODUCTION Accumulating evidence indicates that interleukin (IL)-34 participates in T-cell homeostasis and tolerance due to the ability of IL-34 to trigger apoptosis of Th1, Th17, and Tc1 cells, but spare Th2 cells and Treg. In addition, IL-34 exerts anti-inflammatory effects by impairing leukocyte adhesion and transendothelial migration, and reducing the secretion of proinflammatory cytokines. The aim of our study was to investigate the time course of serum levels of IL-34 during hepatic… CONTINUE READING