Serum IGF-1 and IGFBP-3 levels as clinical markers for patients with lung cancer.

@article{Tas2016SerumIA,
  title={Serum IGF-1 and IGFBP-3 levels as clinical markers for patients with lung cancer.},
  author={Faruk Tas and Elif Bilgin and Didem Taştekin and Kayhan Erturk and Derya Duranyildiz},
  journal={Biomedical reports},
  year={2016},
  volume={4 5},
  pages={609-614}
}
Insulin-like growth factor-1 (IGF-1) and its essential binding protein-3 (IGFBP-3) exhibit significant roles in cellular proliferation, differentiation and apoptosis in numerous malignancies, including lung cancer. The aim of the present study was to determine the clinical roles of the serum IGF-1 and IGFBP-3 levels in lung cancer patients. A total of 80 patients with lung cancer were enrolled in the study. Serum IGF-1 and IGFBP-3 concentrations were determined by ELISA methods. The median age… CONTINUE READING