Serum HOTAIR as a novel diagnostic biomarker for esophageal squamous cell carcinoma

Abstract

Early diagnosis of esophageal squamous cell carcinoma (ESCC) is an important issue to improve the prognosis. HOX transcript antisense RNA (HOTAIR), a long noncoding RNA (lncRNA) expressed from the HOXC locus, has been recently revealed as an oncogenic regulator in ESCC. This study aimed to investigate whether serum HOTAIR is involved in the diagnosis of… (More)
DOI: 10.1186/s12943-017-0643-6

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