Serum HBV DNA as a marker of efficacy during therapy for chronic HBV infection: analysis and review of the literature.

@article{MommjaMarin2003SerumHD,
  title={Serum HBV DNA as a marker of efficacy during therapy for chronic HBV infection: analysis and review of the literature.},
  author={Herv{\'e} Momm{\'e}ja-Marin and Elsa Mondou and M. Robert Blum and Franck Rousseau},
  journal={Hepatology},
  year={2003},
  volume={37 6},
  pages={1309-19}
}
Currently, compounds under evaluation for treatment of chronic hepatitis B virus (HBV) infection are evaluated with liver histology as the primary end point for efficacy. However, because of practical limitations in serial liver biopsies, there is a need for alternate markers to assess efficacy over shorter periods of time. Considering the direct correlation between viral replication and disease progression during human immunodeficiency virus and hepatitis C virus infection, we explored whether… CONTINUE READING
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