Serum FGF21 levels are associated with brown adipose tissue activity in humans

@inproceedings{Hanssen2015SerumFL,
  title={Serum FGF21 levels are associated with brown adipose tissue activity in humans},
  author={Mark J. W. Hanssen and Evie Broeders and Ricardo J. Samms and Maarten J. Vosselman and Anouk A. J. J. van der Lans and Christine Kei Chin Cheng and Andrew Charles Adams and Wouter D. van Marken Lichtenbelt and Patrick Schrauwen},
  booktitle={Scientific reports},
  year={2015}
}
The obesity pandemic has spurred a need for novel therapies to prevent and treat metabolic complications. The recent rediscovery of brown adipose tissue (BAT) in humans made this tissue a possible therapeutic target, due to its potentially substantial contributions to energy homeostasis. Fibroblast growth factor 21 (FGF21) has been identified as a facilitator of cold-induced thermogenesis in humans. Furthermore, pre-clinical studies revealed that FGF21 administration leads to improvement in the… CONTINUE READING