Serum Calprotectin: A Novel Diagnostic and Prognostic Marker in Inflammatory Bowel Diseases

@article{Kalla2016SerumCA,
  title={Serum Calprotectin: A Novel Diagnostic and Prognostic Marker in Inflammatory Bowel Diseases},
  author={Rahul Kalla and N A Kennedy and Nicholas T. Ventham and Ray K Boyapati and A Adams and Elaine R. Nimmo and Micaela Rios Visconti and Hazel E. Drummond and G. Ho and Rebecca J Pattenden and David C. Wilson and Jack Satsangi},
  journal={The American Journal of Gastroenterology},
  year={2016},
  volume={111},
  pages={1796-1805}
}
OBJECTIVES:There is an unmet need for novel blood-based biomarkers that offer timely and accurate diagnostic and prognostic testing in inflammatory bowel diseases (IBD). We aimed to investigate the diagnostic and prognostic utility of serum calprotectin (SC) in IBD.METHODS:A total of 171 patients (n=96 IBD, n=75 non-IBD) were prospectively recruited. A multi-biomarker model was derived using multivariable logistic regression analysis. Cox proportional hazards model was derived to assess the… CONTINUE READING
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