Serum Calcification Propensity Is a Strong and Independent Determinant of Cardiac and All‐Cause Mortality in Kidney Transplant Recipients

  title={Serum Calcification Propensity Is a Strong and Independent Determinant of Cardiac and All‐Cause Mortality in Kidney Transplant Recipients},
  author={D. O. Dahle and A. {\AA}sberg and A. Hartmann and H. Holdaas and M. Bachtler and T. Jenssen and M. Dionisi and A. Pasch},
  journal={American Journal of Transplantation},
  • D. O. Dahle, A. Åsberg, +5 authors A. Pasch
  • Published 2016
  • Medicine
  • American Journal of Transplantation
  • Calcification of the vasculature is associated with cardiovascular disease and death in kidney transplant recipients. A novel functional blood test measures calcification propensity by quantifying the transformation time (T50) from primary to secondary calciprotein particles. Accelerated T50 indicates a diminished ability of serum to resist calcification. We measured T50 in 1435 patients 10 weeks after kidney transplantation during 2000–2003 (first era) and 2009–2012 (second era). Aortic pulse… CONTINUE READING
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