Serum Antibody Levels to the Pneumocystis jirovecii Major Surface Glycoprotein in the Diagnosis of P. jirovecii Pneumonia in HIV+ Patients

@inproceedings{Djawe2010SerumAL,
  title={Serum Antibody Levels to the Pneumocystis jirovecii Major Surface Glycoprotein in the Diagnosis of P. jirovecii Pneumonia in HIV+ Patients},
  author={Kpandja Djawe and Laurence Huang and Kieran R. Daly and Linda L Levin and Judy V. Koch and Alexandra Schwartzman and Serena Fong and Brenna M. Roth and Anuradha Subramanian and Katherine Grieco and Leah Jarlsberg and Peter D. Walzer},
  booktitle={PloS one},
  year={2010}
}
BACKGROUND Pneumocystis jirovecii remains an important cause of fatal pneumonia (Pneumocystis pneumonia or PcP) in HIV+ patients and other immunocompromised hosts. Despite many previous attempts, a clinically useful serologic test for P. jirovecii infection has never been developed. METHODS/PRINCIPAL FINDINGS We analyzed serum antibody responses to the P. jirovecii major surface glycoprotein recombinant fragment C1 (MsgC1) in 110 HIV+ patients with active PcP (cases) and 63 HIV+ patients with… CONTINUE READING

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