Serum Adenosine Deaminase and Cytidine Deaminase Activities in Patients with Systemic Lupus Erythematosus
@inproceedings{Tays2002SerumAD, title={Serum Adenosine Deaminase and Cytidine Deaminase Activities in Patients with Systemic Lupus Erythematosus}, author={Seyithan Taysı and Muhammet Fevzi Polat and Refik Ali Sarı and Ebubekir Bakan}, booktitle={Clinical chemistry and laboratory medicine}, year={2002} }
Abstract We evaluated serum total adenosine deaminase, its isoenzymes adenosine deaminase-1 and adenosine deaminase-2, and cytidine deaminase activities in 24 patients with active systemic lupus erythematosus, and in 26 healthy control subjects, and found the means±SD values to be 21.38±5.96 IU/l, 3.74±2.12 IU/l, 17.72±5.02 IU/l and 17.89±4.62 IU/l, respectively in the patients, and 14.97±4.71 IU/l, 4.01±1.35 IU/l, 10.91±3.91 IU/l and 7.39±3.97 IU/l, respectively in the control subjects. When…
25 Citations
Evaluation of serum adenosine deaminase activity and autoantibodies in systemic lupus erythematosus
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Determination of ADA activity is a reliable, cost-effective, and easy test that can be used as an alternative parameter for diagnosing and evaluating disease activity in SLE patients.
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The findings suggest that serum ADA activity could be a diagnostic marker for SLE; moreover, measuring serumADA activity may be helpful for evaluating and monitoring the disease activity of SLE patients.
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Activity and expression of E-NTPDase is altered in peripheral lymphocytes of systemic lupus erythematosus patients.
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- Medicine
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Two ADA-1 and ADA-2 isoenzymes were detected in the human serum, based on which the two types of urticaria can be differentiated, and the authors acknowledge that modulation of adenosine deaminase activity could influenceUrticaria resolution.
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