Serum Adenosine Deaminase and Cytidine Deaminase Activities in Patients with Systemic Lupus Erythematosus

  title={Serum Adenosine Deaminase and Cytidine Deaminase Activities in Patients with Systemic Lupus Erythematosus},
  author={Seyithan Taysı and Muhammet Fevzi Polat and Refik Ali Sarı and Ebubekir Bakan},
  booktitle={Clinical chemistry and laboratory medicine},
Abstract We evaluated serum total adenosine deaminase, its isoenzymes adenosine deaminase-1 and adenosine deaminase-2, and cytidine deaminase activities in 24 patients with active systemic lupus erythematosus, and in 26 healthy control subjects, and found the means±SD values to be 21.38±5.96 IU/l, 3.74±2.12 IU/l, 17.72±5.02 IU/l and 17.89±4.62 IU/l, respectively in the patients, and 14.97±4.71 IU/l, 4.01±1.35 IU/l, 10.91±3.91 IU/l and 7.39±3.97 IU/l, respectively in the control subjects. When… 

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[Adenosine deaminase].
  • N. Kurata
  • Medicine, Biology
    Nihon rinsho. Japanese journal of clinical medicine
  • 1995
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Overproduction of adenine deoxynucleosides and deoxynucletides in adenosine deaminase deficiency with severe combined immunodeficiency disease.
Elevated dATP levels in lymphocytes and bone marrow, and increased urinary excretion of deoxyadenosine, persisted despite hypertransfusion of the child with irradiated erythrocytes from a donor with normal adenosine deaminase.