Serum 6-beta-naltrexol levels are related to alcohol responses in heavy drinkers.

@article{McCaul2000Serum6L,
  title={Serum 6-beta-naltrexol levels are related to alcohol responses in heavy drinkers.},
  author={Mary E McCaul and Gary Wand and Charles Rohde and Shing M Lee},
  journal={Alcoholism, clinical and experimental research},
  year={2000},
  volume={24 9},
  pages={1385-91}
}
BACKGROUND There is strong evidence for the role of the endogenous opioid system in alcohol reinforcement and consumption; however, recent human laboratory studies and clinical trials have reported mixed effects of naltrexone (a nonselective opioid antagonist) on alcohol-related behaviors. This paper reports a secondary data analysis of a human laboratory study that examines the relationship between serum levels of 6-beta-naltrexol, the major, biologically active metabolite of naltrexone, and… CONTINUE READING

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