Serum 25-hydroxyvitamin D as an independent determinant of 1-84 PTH and bone mineral density in non-diabetic predialysis CKD patients.

@article{Tomida2009Serum2D,
  title={Serum 25-hydroxyvitamin D as an independent determinant of 1-84 PTH and bone mineral density in non-diabetic predialysis CKD patients.},
  author={Kodo Tomida and Takayuki Hamano and Satoshi Mikami and Naohiko Fujii and Noriyuki Okada and Isao Matsui and Yasuyuki Nagasawa and Toshiki Moriyama and Takahito Ito and Enyu Imai and Yoshitaka Isaka and Hiromi Rakugi},
  journal={Bone},
  year={2009},
  volume={44 4},
  pages={
          678-83
        }
}
The role of 25-hydroxyvitamin D [25(OH)D] and fibroblast growth factor-23 (FGF-23) in chronic kidney disease-mineral and bone disorder (CKD-MBD) remains elusive in predialysis CKD patients. From the fact that FGF-23 suppresses bone mineralization in vitro and that 1alpha-hydroxylase is present in parathyroid cells and osteoblasts, they may be associated with bone mass or serum parathyroid hormone (PTH) level. In this cross-sectional observational study, we investigated the potential… CONTINUE READING

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