Serum 25-hydroxyvitamin D and adipose tissue vitamin D receptor gene expression: relationship with obesity and type 2 diabetes.

@article{ClementePostigo2015Serum2D,
  title={Serum 25-hydroxyvitamin D and adipose tissue vitamin D receptor gene expression: relationship with obesity and type 2 diabetes.},
  author={Mercedes Clemente-Postigo and Araceli Mu{\~n}oz-Garach and Marta Serrano and Lourdes Garrido-S{\'a}nchez and Mar{\'i}a Rosa Bernal-L{\'o}pez and Diego Fern{\'a}ndez-Garc{\'i}a and Inmaculada Moreno-Santos and N{\'u}ria Garriga and Daniel Castellano-Castillo and Antonio Camargo and Jos{\'e}-Manuel Fern{\'a}ndez-Real and Fernando Cardona and Francisco J Tinahones and Manuel Mac{\'i}as-Gonz{\'a}lez},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2015},
  volume={100 4},
  pages={
          E591-5
        }
}
CONTEXT The relationship between 25-hydroxyvitamin D [25(OH)D] and obesity and type 2 diabetes is not completely understood. Vitamin D receptor (VDR) expression in adipose tissue (AT) is related to obesity and might be regulated by 1,25-dihydroxyvitamin D3 [1,25(OH)2D3]. OBJECTIVE To analyze serum 25(OH)D and VDR gene expression in AT according to body mass index (BMI) and glycemic status and the effect of 1,25(OH)2D3 on AT according to BMI. DESIGN AND PATIENTS Two cohorts were studied: 1… CONTINUE READING

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