Serum 25-Hydroxyvitamin D Insufficiency in Search of a Bone Disease.

@article{Shah2017Serum2D,
  title={Serum 25-Hydroxyvitamin D Insufficiency in Search of a Bone Disease.},
  author={Sonali Shah and Cherie Y Chiang and Kenneth Andrew Sikaris and Zhong Xian Lu and Minh Q. Bui and Roger Martin Djoumessi Zebaze and E. R. BernsteinJeffrey I. Seeman},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2017},
  volume={102 7},
  pages={
          2321-2328
        }
}
Context Vitamin D "insufficiency" and "deficiency" are defined as serum 25-hydroxyvitamin D [25(OH)D] levels <75 and <30 nmol/L, respectively. We aimed to determine whether these values signal hypocalcemia and hypophosphatemia, secondary hyperparathyroidism, high bone remodeling, low areal bone mineral density (aBMD), microstructural deterioration, or reduced matrix mineralization density (MMD) and so suggest whether bone fragility is present. Methods Concentrations of 25(OH)D, calcium… CONTINUE READING