Serum (-5, -7) proPSA for distinguishing stage and grade of prostate cancer.

@article{Stephan2007Serum,
  title={Serum (-5, -7) proPSA for distinguishing stage and grade of prostate cancer.},
  author={Carsten Stephan and H H Meyer and E Paul and Glen Kristiansen and Stefan A. Loening and Michael Lein and Klaus Jung},
  journal={Anticancer research},
  year={2007},
  volume={27 4A},
  pages={1833-6}
}
BACKGROUND ProPSA has been suggested for the detection of preferentially aggressive prostate cancer (PCa). We report on the use of proPSA and free PSA to enhance preoperative staging and grading. PATIENTS AND METHODS Serum samples from 376 PCa patients within the PSA range 1-25 microg/l who underwent radical prostatectomy were analysed for PSA, free PSA (fPSA) and (-5, -7) proPSA. RESULTS ProPSA was only significantly different between pT2 and pT3 PCa (p = 0.02) in the subgroup of patients… CONTINUE READING