Sertraline in stroke-associated lability of mood.

  title={Sertraline in stroke-associated lability of mood.},
  author={Alistair S. Burns and Elen Russell and H Stratton-Powell and Pippa Tyrell and Padraic O'Neill and Robert VV. Baldwin},
  journal={International journal of geriatric psychiatry},
  volume={14 8},
OBJECTIVE To assess whether a selective serotonin reuptake inhibitor is effective in the treatment of stroke-associated lability of mood. METHODS Twenty-eight non-depressed patients suffering from post-stroke lability of mood took part in an 8-week double-blind randomized placebo-controlled trial of a selective serotonin reuptake inhibitor (50 mg sertraline per day). RESULTS There were statistically significant improvements in a global rating of emotionalism and a specific benefit on… CONTINUE READING