Sertoli–Leydig cell communication via an LHRH-like factor

@article{Sharpe1981SertoliLeydigCC,
  title={Sertoli–Leydig cell communication via an LHRH-like factor},
  author={Richard M. Sharpe and Hamish M. Fraser and I Cooper and Focko F. G. Rommerts},
  journal={Nature},
  year={1981},
  volume={290},
  pages={785-787}
}
  • Richard M. Sharpe, Hamish M. Fraser, +1 author Focko F. G. Rommerts
  • Published in Nature 1981
  • Chemistry, Medicine
  • The primary function of the testosterone secreted by Leydig cells is the maintenance of spermatogenesis and hence fertility1. This action of testosterone is mediated by the Sertoli cells which nourish and support the developing spermatozoa2. As normal Sertoli cell function is so critically dependent on normal Leydig cell function, a regulatory influence of the Sertoli cells on the Leydig cells has been suggested3,4. Indeed, follicle-stimulating hormone (FSH), which acts only on Sertoli cells5… CONTINUE READING

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