Sertindole in the treatment of psychosis in schizophrenia: efficacy and safety

  title={Sertindole in the treatment of psychosis in schizophrenia: efficacy and safety},
  author={C. Tamminga and R. Mack and G. R. Granneman and C. Silber and K. B. Kashkin},
  journal={International Clinical Psychopharmacology},
Evidence from clinical trials supports the claim that sertindole is a potent antipsychotic drug at a dose of 12–24 mg/day. Its action against positive symptoms is as potent as that of the traditional antipsychotic haloperidol. Its action against negative; symptoms is significantly different from that of placebo and quantitatively larger than that of haloperidol. Its most distinctive characteristic is a reduction in motor side effects over a whole range of comparable drug and comparator doses… Expand
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