Sertindole: cardiac electrophysiological profile

  title={Sertindole: cardiac electrophysiological profile},
  author={W. Haverkamp and L. Eckardt and J. Matz and K. Frederiksen},
  journal={International Journal of Psychiatry in Clinical Practice},
  pages={11 - 20}
  • W. Haverkamp, L. Eckardt, +1 author K. Frederiksen
  • Published 2002
  • Medicine, Psychology
  • International Journal of Psychiatry in Clinical Practice
  • QT interval prolongation is the ECG correlate of prolongation of the cardiac action potential (AP). Abnormal or excessive QT interval prolongation may be associated with an increased risk of ventricular tachycardia. This association appears increasingly evident in congenital long QT syndrome and with certain classes of cardiovascular and non-cardiovascular therapeutics. Almost all drugs causing QT interval prolongation inhibit the rapid component of the delayed rectifier potassium current (I Kr… CONTINUE READING
    QTc interval prolongation and antipsychotic drug treatments: focus on sertindole.
    • 49
    • PDF
    Electrophysiological Safety of Sertindole in Dogs with Normal and Remodeled Hearts
    • 68
    • PDF
    Sertindole causes distinct electrocardiographic T-wave morphology changes
    • 45
    Sertindole: safety and tolerability profile
    • 11


    Publications referenced by this paper.