Serrated adenoma of the colorectum undergoes a proliferation versus differentiation process: new conceptual interpretation of morphogenesis.

@article{Jiao2008SerratedAO,
  title={Serrated adenoma of the colorectum undergoes a proliferation versus differentiation process: new conceptual interpretation of morphogenesis.},
  author={Yunjie Jiao and Shin-ichi Nakamura and Tamotsu Sugai and Noriyuki Yamada and Wataru Habano},
  journal={Oncology},
  year={2008},
  volume={74 3-4},
  pages={127-34}
}
OBJECTIVE Serrated adenoma (SA) consists of glands both with intraluminal projection of tall columnar cells, which resemble the terminally differentiated cells in the surface epithelium, and with concave short cells, which resemble progenitor crypt cells of the colon. The aim of this study was to clarify the relationship between the serrated architecture and proliferation/differentiation process in SAs. METHODS The expressions of both terminally differentiated markers, such as p21… CONTINUE READING

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Molecular differences between sporadic serrated and conventional colorectal adenomas.

Clinical cancer research : an official journal of the American Association for Cancer Research • 2004

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