Serotyping of Toxoplasma gondii infections in humans using synthetic peptides.

@article{Kong2003SerotypingOT,
  title={Serotyping of Toxoplasma gondii infections in humans using synthetic peptides.},
  author={J Kong and Michael E. Grigg and Lyle Uyetake and Stephen F Parmley and John C Boothroyd},
  journal={The Journal of infectious diseases},
  year={2003},
  volume={187 9},
  pages={1484-95}
}
To determine whether the characteristics of disease due to Toxoplasma gondii (toxoplasmosis) are dependent on the infecting strain, we have developed an enzyme-linked immunosorbent assay for typing strains that uses infection serum reacted against polymorphic peptides derived from Toxoplasma antigens SAG2A, GRA3, GRA6, and GRA7. Pilot studies with infected mice established the validity of the approach, which was then tested with human serum. In 8 patients who had Sabin-Feldman dye test titers… CONTINUE READING