Serotype-specific immune responses to pneumococcal conjugate vaccine among children are significantly correlated by individual: Analysis of randomized controlled trial data.

@article{Lipsitch2018SerotypespecificIR,
  title={Serotype-specific immune responses to pneumococcal conjugate vaccine among children are significantly correlated by individual: Analysis of randomized controlled trial data.},
  author={Marc Lipsitch and Lucy M. Li and Scott Patterson and James Trammel and Christine Juergens and William C. Gruber and Daniel J Scott and Ron Dagan},
  journal={Vaccine},
  year={2018},
  volume={36 4},
  pages={473-478}
}
BACKGROUND The magnitude of an individual's serotype-specific immunoglobulin G (IgG) response to a pneumococcal conjugate vaccine (PCV) has been associated with the vaccine's protective efficacy against carriage of pneumococci of that serotype, though the relationship with other serotypes needs to be understood. METHODS Using immunogenicity data collected… CONTINUE READING