Serotype-converting bacteriophages and O-antigen modification in Shigella flexneri.

  title={Serotype-converting bacteriophages and O-antigen modification in Shigella flexneri.},
  author={Gwen E. Allison and Naresh K Verma},
  journal={Trends in microbiology},
  volume={8 1},
O-antigen modification (serotype conversion) in Shigella flexneri, which is an important virulence determinant, is conferred by temperate bacteriophages. Several serotype-converting phages have been isolated and preliminary characterization has identified the genes involved in O-antigen modification, and has also provided insight into the molecular biology of these phages. 
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