Serotype 19f multiresistant pneumococcal clone harboring two erythromycin resistance determinants (erm(B) and mef(A)) in South Africa.

@article{Mcgee2001Serotype1M,
  title={Serotype 19f multiresistant pneumococcal clone harboring two erythromycin resistance determinants (erm(B) and mef(A)) in South Africa.},
  author={Lesley Mcgee and Keith P. Klugman and Avril D Wasas and Thora P Capper and Adrian Brink},
  journal={Antimicrobial agents and chemotherapy},
  year={2001},
  volume={45 5},
  pages={
          1595-8
        }
}
One hundred eighteen erythromycin-resistant Streptococcus pneumoniae (ERSP) strains (MICs of > or = 0.5 microg/ml) from five laboratories serving the private sector in South Africa were analyzed for the genes encoding resistance to macrolides. Sixty-seven ERSP strains (56.8%) contained the erm(B) gene, and 15 isolates (12.7%) contained the mef(A) gene. Thirty-six isolates (30.5%) harbored both the erm(B) and mef(A) genes and were highly resistant to erythromycin and clindamycin. DNA… CONTINUE READING
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