Serotonin uptake is largely mediated by platelets versus lymphocytes in peripheral blood cells.

@article{Beikmann2013SerotoninUI,
  title={Serotonin uptake is largely mediated by platelets versus lymphocytes in peripheral blood cells.},
  author={Brendan Stephen Beikmann and Ian D. Tomlinson and Sandra J Rosenthal and Anne Milasincic Andrews},
  journal={ACS chemical neuroscience},
  year={2013},
  volume={4 1},
  pages={
          161-70
        }
}
The serotonin transporter (SERT), a primary target for many antidepressants, is expressed in the brain and also in peripheral blood cells. Although platelet SERT function is well accepted, lymphocyte SERT function has not been definitively characterized. Due to their small size, platelets often are found in peripheral blood mononuclear cell preparations aimed at isolating lymphocytes, monocytes, and macrophages. The presence of different cells makes it difficult to assign SERT expression and… CONTINUE READING
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Differential serotonin

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