Serotonin transporter promoter polymorphism, peripheral indexes of serotonin function, and personality measures in families with alcoholism.

  title={Serotonin transporter promoter polymorphism, peripheral indexes of serotonin function, and personality measures in families with alcoholism.},
  author={Scott F Stoltenberg and Geoffrey R. Twitchell and Gregory L. Hanna and Edwin H. Cook and Hiram E. Fitzgerald and Robert A. Zucker and Karley Y. Little},
  journal={American journal of medical genetics},
  volume={114 2},
A functional polymorphism in the regulatory region of the serotonin transporter gene (5-HTTLPR) is considered to be a plausible candidate gene for anxiety-related personality traits and for alcoholism. Empirical support for the association between 5-HTTLPR and psychological traits has been somewhat inconsistent; however, observations of the functional dominance of the low-activity s-allele over the l-allele have been more consistent. When studying the influence of particular genes on… 

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