Serotonin transporter polyadenylation polymorphism modulates the retention of fear extinction memory.

Abstract

Growing evidence suggests serotonin's role in anxiety and depression is mediated by its effects on learned fear associations. Pharmacological and genetic manipulations of serotonin signaling in mice alter the retention of fear extinction learning, which is inversely associated with anxious temperament in mice and humans. Here, we test whether genetic… (More)
DOI: 10.1073/pnas.1202044109

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@article{Hartley2012SerotoninTP, title={Serotonin transporter polyadenylation polymorphism modulates the retention of fear extinction memory.}, author={Catherine A. Hartley and Morgan C McKenna and Rabia Salman and Andrew Holmes and B. J. Casey and Elizabeth A. Phelps and Charles E. Glatt}, journal={Proceedings of the National Academy of Sciences of the United States of America}, year={2012}, volume={109 14}, pages={5493-8} }