Serotonin transporter gene polymorphisms in patients with unipolar or bipolar depression.

@article{Bellivier1998SerotoninTG,
  title={Serotonin transporter gene polymorphisms in patients with unipolar or bipolar depression.},
  author={Frank Bellivier and Chantal Henry and Andrei Sz{\"o}ke and Franck Sch{\"u}rhoff and Marika Nosten-Bertrand and Josu{\'e} Feingold and Jean Marie Launay and Marion Leboyer and Jean Louis Laplanche},
  journal={Neuroscience letters},
  year={1998},
  volume={255 3},
  pages={143-6}
}
To explore the involvement of serotonin transporter (5HTT) in mood disorder, we studied two polymorphisms of the 5HTT gene (a variable number of tandem repeats in the second intron (VNTR) and a 44 bp insertion/deletion in the 5HTT linked polymorphic region (5-HTTLPR)) in a sample of unipolar and bipolar patients and controls. Homozygosity for the short variant of the 5-HTTLPR was significantly more frequent in bipolar patients than in controls (chi2 = 4.68, d.f. = 1, P = 0.03) whereas there was… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 43 extracted citations

Similar Papers

Loading similar papers…